By now you probably know to call your credit card company before you travel. By letting them know you will be in Venice, Italy or Venice Beach, California makes life easier for everyone. For one thing, you won't have your purchases denied. The credit card company will monitor any purchases not in the areas where you are traveling.
But, what if you lose your credit card? Do you have their number? Be sure to have both numbers, including the international number, handy. Store it somewhere that's easy for you to get to but easy to lose.